Center for Mind, Brain, and Culture

Lecture | Steve Cole | Social Regulation of Human Gene Expression

Episode Summary

Lecture | Steve Cole | Social Regulation of Human Gene Expression

Episode Notes

Relationships between genes and social behavior have historically been viewed as a one-way street, with genes in control. Recent analyses have challenged this view by discovering broad alterations in the expression of human genes as a function of differing socio-environmental conditions. My talk summarizes the developing field of social genomics, and its efforts to identify the types of genes subject to social regulation, the biological signaling pathways mediating those effects, and the genetic polymorphisms that moderate socio-environmental influences on human gene expression. This approach provides a concrete molecular perspective on how external social conditions interact with our genes to shape the functional characteristics of our bodies, and alter our future biological and behavioral responses based on our personal transcriptional histories. (March 25, 2014)